Triflic anhydride may be used to introduce a protective trifluoromethane sulfonyl group. It is a strong activator of hydroxyl groups, for example in glycosidation reactions. It is an efficient promoter for inversion configuration and for nucleophilic substitutions. It may also be used as an activator of phenols or enols for the synthesis of aryl and vinyl triflates.
morelessTriflic Acid
TA, TFOH
Triflic acid belongs to the class of superacids, it is the strongest Bronstedt acid available at industrial scale. It is used as anacidic catalyst in many reactions in organic synthesis (alkylation, esterification, etherification, acylation, isomerization, ethoxylation, cyclization, cationic rearrangement, etc .) and in cationic polymerization. The triflate anion is widely used as intermediate in organic synthesis, since it is an excellent leaving group (up to 30,000 times more effective than tosylate). Due to its uniqueproperties the triflate anion is also an excellent anion for ionic liquids.
| Available in | Asia Pacific, Europe, Latin America, North America. |
|---|---|
| Brand | No specific brand |
| Market(s) | Health, personal and home care, Industry & processing. |
| Market segment(s) | Medical & Pharmaceuticals, Fine chemical intermediates. |
| Applications | Acid catalyst for the industry , Intermediate for liquid crystals , Pharmaceuticals intermediates , Intermediate for organic synthesis |
| Product range | Fluorinated compounds - Fluorinated compounds |
| CAS number | 1493-13-6 |
| Global Business Unit | Aroma Performance |
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Trimethylsilyl triflate is a lewis acid catalyst and a trimethylsilylating agent
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